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Saving Sight



Our November event was all about the eye: Professor Steve Moss, from the UCL Institute of

Ophthalmology, gave an exciting talk, organised in collaboration with ‘Fight for Sight,’ the

Eye Research Charity.


People gathered for a truly cosy evening at the Cittie of Yorke pub. Steve talked us through

eye diseases, how to treat them, and new scientific approaches to save sight.


In his talk, Steve explained the causes of AMD and Glaucoma, which both result in dying

cells. His research identified and led to the production of a fluorescent antibody that can

detect dying cells in the retina. This can help to quantify the efficiency of drugs after 1-2

weeks, instead of having to wait for 2-3 years before effects on vision become apparent.

Steve’s group also investigated excessive blood vessel growth in the retina (a phenomenon

that leads to excessive fibrosis and then loss of sight). Interestingly, excessive blood vessel

growth also happens in cancer. The researchers are working on blocking a protein that

initiates excessive blood vessel growth in both - eye diseases and cancer. If successful, they

will develop a drug that would potentially save the eyesight of millions of people as well as

providing a potential treatment for some types of cancer.


Following Steve’s great talk, we had a very lively discussion about differences in glaucoma

and diabetes-related eye problems; different approaches taken by science funding agencies;

pharma research vs. university research; as well as personal questions regarding eye laser

therapy. The audience was incredibly curious, and Steve did a great job answering all the

questions which the audience threw at him.


Thank you, Steve, for such an amazing talk - and a big thank you to the audience, for being

so curious and for turning this evening into another great success!


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