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Understanding the epidemiology of Zika virus

Tuesday, 27th of September 2016

 

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Following the introduction of Zika in Brazil in 2015, the virus continues to spread across Latin America. However, our understanding of the transmission dynamics and epidemiology of this new threat remains poor.
Although typically thought to cause a mild disease, the perception of the public health threat posed by Zika changed dramatically in late 2015 when a surge in microcephaly cases in new-borns was seen in areas of Brazil following widespread Zika transmission earlier that year. Evidence for a causal link between Zika infection and microcephaly and other serious congenital anomalies is now compelling, and prompted the World Health Organization to declare Zika a public health emergency of international concern in February 2016. However, given the uncertainties in the dynamics of Zika transmission, it is far from clear how policymakers should best respond.
After introducing the epidemiological situation and public health strategies implemented, we will provide estimate of the transmission potential of Zika based on incidence of reported cases as well as incidence of microcephaly. We will also present a simple model of Zika dynamics and highlight some key predictions concerning future epidemics and the potential impact of interventions. Finally we will present some of the ongoing research projects we are conducting to address the current uncertainties.

 

Dr. Pierre Nouvellet is Lecturer in Infectious Disease Modelling, at the MRC Centre for Outbreak Analysis and Modelling in the Department of Infectious Disease Epidemiology (Imperial College London).
His research interests broadly lie in quantitative methods applied to infectious disease epidemiology. A key aim is to develop quantitative modelling tools and techniques to assimilate, analyse and integrate data from the diverse sources. The goals are to improve disease surveillance, control, preparedness and intervention.
With a background in ecology, his interests in epidemiology initially grew around vector-borne and zoonotic diseases (e.g. Chagas disease and rabies). He has since also developed strong research interests in emerging diseases and rapid outbreak responses (e.g. MERS-CoV, Ebola, Zika), developing transmission models used to gain biological and epidemiological insights and to underpin risk assessment and contingency planning.
 

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